The digestion and absorption of acetyltryptophan.
نویسندگان
چکیده
In a recent paper (1) data were presented to show that acetyl-n-tryptophan was excreted in the feces, whereas acetyl-L-tryptophan was preferentially absorbed and utilized. Three possibilities were presented to explain the absorption of the L isomer: (a) It is deacetylated when passing through the gastrointestinal tract, (b) it is absorbed as acetyl-L-tryptophan and then deacetylated, and (c) both (a) and (b) may occur. This paper presents experimental data taken in an attempt to learn more about the mechanism of digestion and absorption of acetyltryptophan.
منابع مشابه
Absorption studies on tryptophan and acetyltryptophan.
Many investigations have demonstrated that amino acids are absorbed by enzymatic processes (l-3). Recent investigations on the fate of ingested acetyl-L-tryptophan (4) showed that the rate of absorption of this isomer is much slower than that reported previously for an equivalent amount of free n-tryptophan (5). du Vigneaud et al. (6) found, however, that the acetylated analogue is utilized equ...
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عنوان ژورنال:
- The Journal of biological chemistry
دوره 223 1 شماره
صفحات -
تاریخ انتشار 1956